Betta Pharmaceuticals said its pan‑RAS inhibitor BPI‑572270 capsule completed first‑participant dosing in an Australia Phase I/II study today. Preclinical data show strong inhibition in tumor cells and xenograft models with diverse RAS mutations (KRAS, NRAS, HRAS, including G12X, G13X, Q61X) across pancreatic, non‑small‑cell lung and colorectal cancers, and report favorable pharmacokinetics and safety.

Iranian parliament speaker Ghalibaf said Israel is attempting to drag the United States into an endless war with Iran that would entangle any current or future U.S. president, Republican or Democrat. He said unless the U.S. abandons an "Israel-first" mindset, the United States and its allies will inevitably enter a dark era.

China's deputy UN ambassador Sun Lei said the Ukraine issue is at a critical juncture, noting recent interactions among key stakeholders have produced some positive signals. He said China supports efforts toward peace, urged parties to move toward each other to sustain momentum and pursue an early political solution, and called for safeguarding humanitarian standards, cooling tensions, seizing the negotiation window, addressing root causes and seeking lasting peace.